{"id":792,"date":"2026-06-23T16:08:39","date_gmt":"2026-06-23T07:08:39","guid":{"rendered":"https:\/\/www.ulvac-phi.com\/surface-analysis\/applications\/biomedical\/"},"modified":"2026-07-13T14:29:12","modified_gmt":"2026-07-13T05:29:12","slug":"biomedical","status":"publish","type":"page","link":"https:\/\/www.ulvac-phi.com\/en\/surface-analysis\/applications\/biomedical\/","title":{"rendered":"Biomedical"},"content":{"rendered":"\n<article class=\"p-biomedical\">\n    <div class=\"p-biomedical__inner\">\n\n        <p class=\"p-biomedical__lead\">The ability to study metal and polymer surface chemistry and correlate it with biocompatibility is a routine application of surface analysis equipment. An emerging application is the study of proteins and other organic materials for the development of biosensor technology and studying mechanisms to promote cell growth.<\/p>\n\n        <div class=\"p-biomedical__body\">\n\n            <h2 class=\"p-biomedical__title\">Surface characterization (XPS, TOF-SIMS, AES)<\/h2>\n            <p>Surface composition is critical to biomedical device performance. XPS surface analysis provides quantitative chemical state information that can be used to evaluate and monitor surface composition. TOF-SIMS surface analysis provides molecular structure information and trace element detection that is not available via XPS. AES surface analysis provides high spatial resolution surface characterization with elemental and limited chemical state information.<\/p>\n\n            <figure class=\"p-biomedical__figure\">\n                <img decoding=\"async\" src=\"\/wp-content\/themes\/ulvac-phi\/assets\/img\/page\/biomedical\/pg_biomedical_surface-analysis.gif\" alt=\"Biomedical Surface Analysis (SXI and micro XPS spectra of coronary stent surface)\" width=\"345\" height=\"459\" loading=\"lazy\" \/>\n                <figcaption class=\"p-biomedical__cap\"><span class=\"p-biomedical__capNum\">Fig. 1<\/span>: X-ray induced secondary electron image (SXI) and micro X-ray photoelectron (XPS) spectra.<\/figcaption>\n            <\/figure>\n\n            <p>Localized contamination on the coronary stent surface was identified by SXI. Micro XPS spectra of the contaminated region indicated that the contamination was an organofluorine compound.<\/p>\n\n            <figure class=\"p-biomedical__figure\">\n                <img decoding=\"async\" src=\"\/wp-content\/themes\/ulvac-phi\/assets\/img\/page\/biomedical\/pg_biomedical_tof-sims.gif\" alt=\"TOF-SIMS Surface Analysis (TOF-SIMS mass image and chemical structural formula of biosensor surface)\" width=\"295\" height=\"427\" loading=\"lazy\" \/>\n                <figcaption class=\"p-biomedical__cap\"><span class=\"p-biomedical__capNum\">Fig. 2<\/span>: TOF-SIMS images of a biological ligand used in the fabrication a biosensor.<\/figcaption>\n            <\/figure>\n\n            <p>The distribution of ligands (substances that specifically bind to biological materials) used in biosensors was clearly demonstrated by TOF-SIMS imaging.<\/p>\n\n        <\/div>\n    <\/div>\n<\/article>\n\n","protected":false},"excerpt":{"rendered":"<p>The ability to study metal and polymer surface chemistry and correlate it with biocompatibility is a routine application of surface analysis equipment. An emerging application is the study of proteins and other organic materials for the development of biosensor technology and studying mechanisms to promote cell growth. Surface characterization (XPS, TOF-SIMS, AES) Surface composition is critical to biomedical device performance. XPS surface analysis provides quantitative chemical state information that can be used to evaluate and monitor surface composition. TOF-SIMS surface analysis provides molecular structure information and trace element detection that is not available via XPS. AES surface analysis provides high spatial resolution surface characterization with elemental and limited chemical state [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":696,"menu_order":37,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-792","page","type-page","status-publish","hentry"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"The ability to study metal and polymer surface chemistry and correlate it with biocompatibility is a routine application of surface analysis equipment. An emerging application is the study of proteins and other organic materials for the development of biosensor technology and studying mechanisms to promote cell growth. Surface characterization (XPS, TOF-SIMS, AES) Surface composition is\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.ulvac-phi.com\/en\/surface-analysis\/applications\/biomedical\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.9\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"ULVAC PHI\u3000\u30a2\u30eb\u30d0\u30c3\u30af\u30fb\u30d5\u30a1\u30a4\u682a\u5f0f\u4f1a\u793e - \u8868\u9762\u5206\u6790\u88c5\u7f6e\uff08XPS\u30fbAES\u30fbTOF-SIMS\uff09\u30e1\u30fc\u30ab\u30fc\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Biomedical - ULVAC PHI \u30a2\u30eb\u30d0\u30c3\u30af\u30fb\u30d5\u30a1\u30a4\u682a\u5f0f\u4f1a\u793e\" \/>\n\t\t<meta property=\"og:description\" content=\"The ability to study metal and polymer surface chemistry and correlate it with biocompatibility is a routine application of surface analysis equipment. An emerging application is the study of proteins and other organic materials for the development of biosensor technology and studying mechanisms to promote cell growth. 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